Smeags on 25 March 2011
The only thing I've noticed from switching the 3D slider from 0 to active is a slight eye strain as your eyes adjust to the 3D effect. Seconds later my eyes were just fine and enjoying PilotWings Resort (the Best Buy demo). For that game, I had the slider a little lower than halfway, and it suited me just fine.
I played for a good ten mintues and felt no issues while doing so. So other than the inital eye strain from going from 2D to 3D, it's all good in the hood.
So "no" I guess.
