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There's no way of knowing but there's a chance.

Pokemon will, but you won't count it.
Um Dragon Age 2... combined with PC didn't DA:1 sell 4 or more million including PC. Could Do it.
Zelda
Basically any Nintendo Wii Game that doesn't have samus in it.
Black Ops
Hell, I'd say Little Big Planet 2 has a small chance.
Metal Gear Solid Rising... (isn't that coming out next year it has a chance.. And it's a multiplat... MGS4 wasn't)