Rainbird on 16 September 2010
http://kotaku.com/5639264/mafia-ii-sets-an-f+bomb-record-[nsfw]
House Of The Dead: Overkill previously held the Guinness-certified World Record for most uses of the F-word in a video game, with 189. Mafia II has whacked that target. Rooster Teeth's Achievement Hunter compiled all 200. Language very NSFW.
Achievement Hunter: World Record F-Bombs [Rooster Teeth]
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Not exactly the game I would have expected to take the record, but what the hell. 
