They're all good in their own way. And the best part was their games, so I wouldn't be able to pick one over the other.
If I chose purely based on Quantity of games, the NES would win. However, the SNES has both a ton of good games and Quality games; just not as many as the NES. Yet, the N64 had arguably one of the best ratio of quality games and quantity. Yet you can't count out the GameCube because even though it had far fewer games, some of them are still remembered as the best to this day. And the Wii, like the GameCube, is turning out to have some of the best games ever made, but the list has quickly outgrown even the GameCube.
So in reality, I couldn't choose one.
Also, as it has been pointed out, the DS isn't a home console. However, if it was, it would easily win.
Six upcoming games you should look into:
