Trying to give a honest opinion here, I think it won't, not because the game is not good, but because I don't see the game appealing to those people who have yet to buy an Xbox 360. I have seen trailers from the game and I have liked what I have seen, even though I feel like it is a PG-13 version of Silent Hill.
To me the games that are system sellers this generation, or at least huge system sellers, are those that are follow-ups to great franchises or that offer a great or enjoyable multiplayer experience which draws people to buy systems in order to play with friends.
This doesn't mean that the game won't sell well, but to me it seems like those who will buy it are those who already have a 360 and want a good exclusive in their library.
I won't get it for obvious fanboyismic reasons.
Nintendo is selling their IPs to Microsoft and this is true because:
http://gamrconnect.vgchartz.com/thread.php?id=221391&page=1
