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Well there's a few things I can think of that aren't just casual games as well. I could think of quite a few for those.

The hardcore gamers would be a lot harder to create for. Some things that come to mind are, steadiness in FPS where as if you aren't relaxed the scope shakes on you.
A horror game in which your heartbeat represents the noise for something to hear you (if you have seen Van Helsing and remember the part where Dracula talks about his heartbeat)

In american football in can see this used for keeping calm in blitzed situations... although not likely

I see the vitality sensor as being used as an optional add-on for most games, like how the wii-balance board is now.