I don't play a lot of games ..
Best Graphics -call of duty 4
Best Sound Effects - Mass effect
Best Replay Value -mass effect
Best Music/Soundtrack - may be of the music games .. i don't know
Best Story - mass effect / halo 3
Best Multiplayer -halo 3
Most Innovative Feature in a Game: I dont know what it is mean ..sorry
Most Innovative Game: same thing
In specific catagories:
Best First/Third Person Shooter: Halo 3
Best Racing Game:Forza 2
Best RPG: Mass Effect
Best Action/Adventure Game:
Best XBLA Game:
Game of the Year (all genres): Mass Effect