Best Graphics: Super Mario Galaxy
Best Sound Effects: Super Mario Galaxy
Best Replay Value: Super Mario Galaxy
Best Music/Soundtrack: Super Mario Galaxy
Best Story: Metroid Prime 3
Best Multiplayer: Medal of Honor Heroes 2
Most Innovative Feature in a Game: Gravity in Super Mario Galaxy
Most Innovative Game: Super Mario Galaxy
In specific categories:
Best First/Third Person Shooter: Resident Evil 4
Best Racing Game: Excite Truck
Best RPG: Super Paper Mario
Best Action/Adventure Game: Zak and Wiki
Best Virtual Console Game Game: Super Mario World
Game of the Year (all genres): Super Mario Galaxy
Turd/Letdown of the Year: Soul Calibur
Feel Free To Add Me Tag: LISMDK - Extremely bad taste in music