My expectations:
-DSi XL, Picross 3D, S&P2 dates (Q2)
-Monster Hunter Tri & dragon Quest IX rollout
-new Metroid OM, Spawn Smasher, etc media
-Mario Galaxy 2, Xenoblade, Golden Sun DS, etc reconfimations
-Freind Connection for the west
-something on Zelda, maybe a title/logo/art, but no actual game media
My (reasonable) hopes:
-DSi Virtual Console (GB, GBA, GG, NGP, etc)
-The Last Story reveal
-more localizations (Reginleiv, Last Window, PokePark, etc)
-Nintendo+Level-5 tie ups (Layton 3, Inazuma Eleven, Ninokuni, etc)