It's a little early to be worrying about 2011, after all it is Nintendo, but so far we 'know' about:
Zelda Wii (hope I'm wrong)
Retro title
Pikmin 3 (unless Miyamoto was lying to us)
Dragon's Quest
The Last Story
Xenoblade
That's a pretty good start I think and there are bound to be other titles not yet announced or hinted at.