"I just want to figure out why games like Madworld, No More Heroes, etc etc "struggle" on the Wii."
What the hell makes you think they would have sold better on other systems? And don't give me tentatively related games as proof of otherwise (just in case you were going to do that). For Madworld, show me a brawler with an atypical art style that sold better. For No More Heroes, show me a Cell Shaded hack and slash game with a lot of meta moments that sold better, and then explain why it's the first Suda 51 game getting a sequel equals "struggling".
The problem is you have fallen for the myth that niche titles sell less because they are on the Wii, and not because they are niche.
A flashy-first game is awesome when it comes out. A great-first game is awesome forever.
Plus, just for the hell of it: Kelly Brook at the 2008 BAFTAs