Id say the PS3 because of Demon's Souls. That is all
1) PS3 (See above)
2) DS (Just the sales of the hardware alone should put it here, but even with the piracy its still selling games)
3) Xbox360 (Sales of the hardware might be down but damn can they move software)
4) WII (First/Second party support is great and console sales are damn good, they just have to figure the 3rd party thing out)
5) PSP (I love it but man has it been rough this year)
...
6) PC (Dragon Age is awesome on the PC but no SC2 beta this summer + Activision taking over blizzard = bad...very bad)