If you´re talking about Wii I agree about a "true Pokemon" game being huge but I see it doing better in 2d saleswise. Besides this one I think Nintendo could try to achieve another new casual title that will reach the massmarket like the Wiiseries. It´s hard to do but Nintendo are masters of this. Perhaps something with the new Vitality Sensor? (I know it looks stupid and like a gimmick but you never know with Nintendo)
For DS i believe Pokemon HG/SS has a nice shot. It´s almost at 3 million in Japan alone. Tomodachi Collection is a phenomena in Japan and I truly think this game could be huge if it´s released overseas as well. 10 million like Animal Crossing WW is possible for that one if all goes well.







