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of course RE5 can be done on the wii, it's just won't be the same game that all of are us know.

If it does eventually get ported, then don't expect the same exact game, compromises will be taken, not only on the graphics department but also on the physics, AI, and amount of enemies, it's pretty much the typical stuff, take a look at dead rising to give ya an idea of the difference from the original 360 one to the wii one. The only thing that can remain the same is really the gameplay mechanics.