Just finished Uncharted 2...And yes my Ps3 froze..

[mtlca66]

Kantor said:

Let me guess: It was in the room where the guardians fight the mercenaries, everyone is dead, and you picked up a weapon?

Common bug. Don't worry, when you load, you're in the next room. You haven't missed anything. But there's plenty of reason to play it again.

just fell victim to this :(