Those screens for Uncharted 2 do not justify it's jaw-dropping visual fidelity.
Alan Wake looks like it's going to have some awesome weather/lighting effects and some nice big free roaming environments. It's also probably going to be a great game, but at the moment, Uncharted 2 trumps it in the graphics department.
Honestly, there isn't much for the foreseeable future that can challenge Uncharted 2 in my opinion.