It will be the end of the ratchet and clank future series (ToD, Q4B and ACiT), it will probably also mark the last Insomniac developed ratchet game this generation since i would expect Resistance 3 to come out 2010 and possibly new IP in 2011, with PS4 in 2012 with new ratchet(PS4) + 2nd game in the new IP's series(PS3).