Teh Cell can't handle it. Uncharted 3 will make slims explode.
On a more series note: This happened around the time GTA4 and CoD4 launched as well. This games were heavily played and sold huge. Systems mess up everyday, they just happened to be playing these games at the time, then people post about what they were playing when their system broke. End result: ZOMG X game breaks systems!!!
However I've personally had my system run really hot playing CoD4 and GTA4 compared to other games. Just by playing and messing around for a few hours and you'll see that GTA4 is a very demanding game for processors [heck, look at the specs for the PC version]. As for CoD, I just assume it wasn't optimized that well. The game was released in the systems first full year so that's understandable.
4 ≈ One
