3d Mario doomed? Hell no! But you make some interesting points. I doubt Nintendo will choose to focus on one or the other. They'll probably (and hopefully) come out with a mix of both thus giving more variety to the brand on an ongoing basis and reducing the chance of IP fatigue (if that's even possible with a franchise as successful as Mario).
I love the thought of having one 3D and one 2D console Mario game per generation!
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