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41. Madden NFL 08 - 5.15 million sold

(2.41M for X360, .94M for Wii, .93M for PS3, .65M for PSP, .22M for DS) Madden totals including last gen systems: Madden 08: 7.63M Madden 09: 7.42M Madden 10: 3.32 so far
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42. Resident Evil 5 - 4.96 million sold
(2.56M for PS3, 2.40M for X360) Another game which has held fast since September. Should do well over the holidays, since it has not had a holiday season yet.
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43. Pro Evolution Soccer 2008 - 4.94 million sold

(1.74M for PS3, 1.22M for X360, 1.04M for Wii, .85M for PSP, .09M for DS) Sept: The PS2 version sold a bonkers 3.42 million, meaning this game reached over 8 million buyers. PES 2009 has reached less than 6 million, and less than 4 million on current gen systems. 2009 has now reached 6 million total, but still below 4 million on current systems. PES 2010 is at 1.83 million so far.
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44. MySims - 4.93 million sold

(3.46M for DS, 1.47M for Wii) Sept: There was no banner for this game, so I took the pic for MySims Kingdom. Kingdom was the 2008 sequel which sold almost 2 million. Annual sequels are okay, but in 2009, EA has released MySims Party, Racing, and Agents. Why make a better game when you can release a different spin-off in 4 consecutive quarters?
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45. Carnival Games - 4.68 million sold

(3.49M for Wii, 1.19M for DS) Carnival Games has actually gained a spot since September. I believe it now retails for just 10 bucks, but one wonders why there was no real follow-up game.
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46. WWE SmackDown! vs. RAW 2008 - 4.67 million sold

(1.44M for X360, 1.16M for PS3, 1.04M for PSP, .93M for Wii, .10M for DS) Sept: And 2 million more for PS2. This was the first version of WWE to come out for Wii, PS3 and DS, and outsold the 2007 edition by over 3 million copies. Too bad for THQ, those new audiences did not return for the 2009 edition, which also sold 3 million less than this game.
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47. Rock Band - 4.65 million sold

(2.41M for X360, 1.34M for Wii, .90M for PS3) Sept: The PS2 version sold another 700K. This game clearly lost the battle with Guitar Hero III, but still changed music games forever by introducing the full band concept that Guitar Hero has copied ever since. Rock Band 2 did not sell enough to make this list, and with the starts that The Beatles and Guitar Hero 5 have gotten off to, maybe no more band games will.
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47. (tie) The Simpsons Game - 4.65 million sold

(1.41M for DS, 1.00M for 360, .93M for Wii, .71M for PS3, .60M for PSP) Sept: 1.2 million more for PS2. All told, this game sold similarly to Simpsons: Hit and Run from 2003, which topped 4 million units on PS2 alone. The VGC database also lists a 1.5 million selling Simpsons Wrestling for original PlayStation, and of course we all remember 1991's classic co-op arcade brawler.
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49. The Legend of Zelda: Phantom Hourglass - 4.55 million sold

Sept: Zelda's biggest shake-up since Ocarina of Time. It failed to have the explosive reception of that game, so it probably does not point to the future of the series on Wii, but it did well enough to earn a DS sequel.
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50. Pokémon Mystery Dungeon: Explorers of Time / Darkness - 4.50 million sold

Sept: The most successful of the dungeon crawler series where you play as the Pokemon. We are well past the DS games that individually propelled hardware sales, but the DS software environment is so healthy, even the 13th best-selling DS game makes this list.
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