Starfox Wii with the Wii Remote held vertically and used as a joystick would be amazing.
As would Blast Corps Wii, where you can get into a mech and punch buildings down with motion control (unfortunately, Blast Corp is a Rare IP, so we're not gonna get it : ( )
Wii has more 20 million sellers than PS3 has 5 million sellers.
Acolyte of Disruption