I would love to see a new Starfox or a sequel to Donkey kong 64(know that ain't happening but i can keep dreaming)
A new shadowman would indeed be cool, but then it needs to be multiplatform
also a new banjo...but then on the system where its meant to be.. if you know what i mean
and last but not least, the only game that was fun on the playstation, and probably better than everything beyond, Crash Bandicoot
Edit: I almost forgot one of the coolest PC games ever, Sacrifice.