"I am speaking of a game where evolution happens. You just help it along. (SPORE you control evolution)'
Try another one of Will Wright's creations: SimEarth.
That was what he originally wanted to do with Spore, but technology back then simply didn't allow that degree of complexity.
Despite it being numbingly boring, it did exactly what you are talking about: helping evolution along. Hell, you didn't have to really do anything if you didn't want to, and the game would just take over.
I let the game run overnight once and when I went back and checked, molluscs discovered fire, built their own spaceships and went off colonizing other worlds.