I think The Conduit will suffer, as their seems to be a greater value in splitscreen play for Wii games than for HD games.
And since I got my greasy hands on Killzone 2 today, I can safely say that I would have it no other way! For every time you get annoyed at a framerate drop and a small stall in the game to load (both of which I have so far only seen in the beginning of the game), there are going to be so many other times where you will marvel at it, and I would lovingly trade in splitscreen play to have Killzone 2 be what it is.
But I can't understand why so many people seem to think that splitscreen (online or not) is of such low importance. Sure, it might be more annoying to play a game on half a screen, but the splitscreen coop is the only reason I will ever buy RE5 for example. Army of Two would have been a disastrous failure without it as well, and having online coop in R2 means a hell of a lot for me and my buddies.
Games that are built with splitscreen in mind will usually be all the better for it, but it is hardly needed in every game these days.







