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I found Carnival Games to be very enjoyable.

Mario Party 8 is a good choice, but you'll probably have people sitting off for a while, and you might have to explain the game/directions.

Mario and Sonic at the Olympic Games is fun, and easy to get a hold of, since they show you the directions (but you'll have to unlock games in here as well, so that'll depend on how much time you have before the trip).