From my understanding, via OXM, Resident Evil 5 does have a control option that allows for run & gun, Dead Space-style game play. If that's true, everyone needs to at least give the game a try.
Otherwise, it felt like Reisdent Evil 4: Co-Op with Ada
Which may or may not be good for you. RE4 lacked horror, but gained a much longer, and very satisfying game.
Back from the dead, I'm afraid.