The gameplay looks a little tedious, but from some of the new videos shown, the humor seems to be quite awesome!
This game could turn out to be one of those few really funny games
This movie shows the humor pretty well
http://ps3.ign.com/dor/objects/14277732/matt-hazard/videos/eatlead_hazardvsJRPGhero_012309.html
EDIT: Actually, come to think of it, shooters have always been difficult to judge in gameplay from videos alone. But that bossfight in the video I posted doesn't seem very engaging.