Diablo 3 will be awesome but won't be out this year.
Starcraft 2 and Demigod are on my radar this year. There will be a couple more that i'm interested in as well.
Left4dead DLC will probably be my PC GOTY, lol.
Demon's Souls Official Thread | Currently playing: Left 4 Dead 2, LittleBigPlanet 2, Magicka