Depending on how much I liked the game, I either do it again immediately, get annoyed and don't play for a few days or weeks, or just don't bother with it again.
It happened to me just as I was landing on that lost planet in Kotor where you first confront Bastila--my save got corrupted, and I'll admit I actually cried a bit because I was so emotionally involved in that story. Good thing I kept the autosave, but that was still a few hours of lost progress. XD







