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If you see the top 25 "The best selling videogames of all time" you can see Nintendo has 21  of the top 25 the only videogames not from Nintendo are 2 GTA , The Sims and GT3.

Edit: 10 of the top 25 are from this gen(Wii and DS)

Here is the complete list

Name Console Publisher Japan America Others Total
Wii Sports Nintendo 3.38 20.89 16.25 40.52
Super Mario Bros Nintendo 6.81 29.52 3.91 40.24
Pokemon Red / Green / Blue Nintendo 10.24 11.44 9.70 31.38
Tetris Nintendo 4.24 23.55 2.47 30.26
Duck Hunt Nintendo 0.28 27.34 0.69 28.31
Pokemon Gold / Silver Nintendo 7.22 9.14 6.75 23.11
Nintendogs Nintendo 1.70 8.41 11.26 21.37
Super Mario World Nintendo 3.55 12.97 4.09 20.61
Wii Play Nintendo 2.65 10.04 6.99 19.68
Super Mario Land Nintendo 4.19 10.99 2.96 18.14
New Super Mario Bros Nintendo 5.53 6.68 5.93 18.14
Grand Theft Auto: San Andreas Rockstar Games 0.41 8.82 8.38 17.61
Super Mario Bros 3 Nintendo 3.84 9.69 3.75 17.28
Pokemon Diamond / Pearl Nintendo 5.86 6.44 4.92 17.22
Brain Training Nintendo 3.99 4.24 8.20 16.43
The Sims Electronic Arts 0.00 11.39 4.69 16.08
Pokemon Ruby / Sapphire Nintendo 5.40 5.74 4.26 15.40
Gran Turismo 3 A-Spec Sony Computer Entertainment 1.89 7.13 5.85 14.87
Pokemon Yellow Nintendo 3.16 5.98 5.50 14.64
Grand Theft Auto: Vice City Rockstar Games 0.47 8.20 5.53 14.20
Mario Kart DS Nintendo 3.44 5.08 5.22 13.74
Wii Fit Nintendo 3.03 5.18 5.51 13.72
More Brain Training Nintendo 5.14 3.16 5.19 13.49
Mario Kart Wii Nintendo 2.00 5.77 5.65 13.42
Super Mario 64 Nintendo 1.92 6.87 3.10 11.89