In terms of technology....Super Mario Galaxy. This isn't even a competition right now. No other Wii game makes use of the TEV in the Wii like Galaxy does (actually only a few other games use it at all). Many of the modern shading techniques used on PC's and the HD console was used in Galaxy and it ran in progressive scan at 60 fps with zero slowdown.
Artistically, there are several including the above named title.
The rEVOLution is not being televised