SNES - DKC (Literally my first owned game, might be why).
PS1/N64 - Mario 64's scope alone, or playing in Midgar or MGS1 Soldier following your footsteps in snow
PS2/GC - I would say just the joy of Smash, it will never leave me.
PS3/Wii/360 - Lost Planet on the HD screen for the first and/or Wii Sports Boxing
PS4/WiiU - This one I don't really have one, nothing has made me have that sense of wonder or amazement, I am hoping Ghost of Tsushima will.
Switch - Breath of the Wild, honestly what I would give just to experience that world again, it felt like the old days where wonder was around every corner.