My biggest irk with RE5 is how they killed off Ozwell E. Spencer without a second thought. I mean, he was the biggest unknown in the whole series... and one of the last ties to the Raccoon City incident. But they just kill him off... in a cutscene.

So much wasted potential.

RE has never made any sense, so that wouldn't be too out of place XD

Yeah.  In RE1 on the PS1, Wesker got torn in half by the Tyrant.  He recovered well.

True, the plot could work. I just think the best end for Wesker would be to extend the hand of friendship, thus overcoming the virus. that has never happened in RE.

That was good but the last part was too cliched as well (wait why am i doing this? oh i love you guys!)

In the end they could have killed off Sheva...I actually thought she was going to die when wesker was hanging on to her in the plane...flashbacks and all.....then bam QTE. It would have been more touching if she died