If evolution happens (evolved CELL, similar/new NVIDIA CGPU or whaterver for a video card) PS3 full compatibility is sure to happen. And with PS2 games, quite possibly, being released on PSN (GOW already prooves it can be done) PS2 will problably be. As PS1 are still playable on Slim, I think that it will be in there also.
So, Sony may end up being with the only machine that can play nearly 20 years of gaming when they lauch PS4, with a reasonable price to boot. Amazing feat if it turns out to be truth. AS the other features (card things, more USB ports and the sort) I dont really miss it. But lets take that the PSEye camera will take one port (the PS wands are bluethoot to it) and so, it may have 2 to 4 USB (3.0? maybe...). Lets the future come!
The one thing I dont expect to see Sony doing is a 500-600 USD price tag ever again.