I have completed Vet mode on Res 5 and finding Pro mode a tad 'difficult' with the almost instant 1 hit deaths.  Can anyone suggest any tips in this mode.  I'm currently mainly using the rifle for 1 hit kills still.  I have heard that the starter weapons max out into a Gat gun, Sawed off shot gun and others which sounds nice.  But really I'm looking for survival tips rather than relying on someone in duo!

u can go and replay certain chapters on easy to collect ammo and money and then go back to pro mode b/c the game saves ur inventory at all times

Just unlocked it today. You have me nervous about playing on that level!

I used the Infinite Rocket Launcher to nuke my way through large chunks of it, and unlimited ammo magnums to shoot through a good bit more.

Anyways, remember it's not always necessary to fight every enemy; sometimes rushing for the is more practical. Like at the end of 2-2 before the boss, you can try to push the dumpster after killing the near-by enemies and get it moved before the next wave attacks.

I also find rushing at certain points and put you in a good position to kill bottlenecked enemies. Like after the part in 5-2/5-3 (Forget which) after you ride across the gap on the moving platform rush to the control room. The Rocket Launcher enemies will both miss and you can get a great view of them and the door a bunch of baddies are about to file out of before they can.

Also it’s important to play smart and know the best routes and ways around major annoyances. In 6-1 one, sniping all the enemies on the crane lets you skip the whole caged Sheva thing. At the end of 3-1 just ignore the magnum and use the stairs to skip over the trap and head for the bridge controls. This will force the baddies to spawn, including one of the giants and you can use a grenade or rocket to quickly wipe them out, then move forward and 180 to kill everyone as they file in through the narrow trench.

If you’re using an A.I. partner, give them either a good one-hit kill weapon or a machine gun. They aimbot, so the powerful weapons like magnums and rifles usually mean free kills, while maxed out machine guns can usually stun enemies for you to kill. Don’t forget to occasionally switch your partner to attack mode. In attack mode they tend to move ahead of you and make good bait to flush out annoying enemies hiding around corners. (Just make sure you have something to heal her with.) Sometimes they’ll even do a lot of the killing themselves if their weapon is up to par.

I don’t recommend the gatling gun, at least not for professional mode. The gatling gun is slow to start and lacks punch on professional. Except for killing reapers, it’s usually not worth the hassle.

On pro mode I recommend
1) Unequip the vests, they are useless. Maybe you you get an extra hit on dogs, but most of the time they just waste inventory space.
2) Avoid special weapons, they suck. The Minigun and bow are useless.
3) Get infinite ammo for the strongest shotgun, (900 attack) for the PS1, the best magnum (it go through armored enemies) and rockets. Use shotgun for crowd control, Sniper for bow enemies and distant enemies, magnum for close quarter combat (armored and tough enemies and rocket launcher for everything. Most bosses die in one hit from the RL and you can spam it on close enemies. You can even kill very close enemies with the RL as long as you aim at the floor (2 meters seems to be the magic distance).

shottie, magnum, sniper. another magnum on sheva is the best option.
landmines are useful for very many areas when you know the specific path of something, like the licker area after the temple where you need to push the dumpster.
Most areas have a special trick to solving it easily. Remember, professional is about beating the game, not getting money or killing enemies.

If you wanna do it without infinite ammo, I've been able to beat most parts with the strong sniper rifle, land mines and nades.

Just finished yesterday...gold is mine! Well my brothers as I helped him :)

Troll was hardest boss I found, wesker was noty that bad in the end. Jill was a bit of a pain as 1 hit deaths became common place... Flash sorted that out.

Oh, unlocked most of the inf ammo for sniper, machine gun, max triple shot pistol, and shotgun. Only need to finish the game with 'S' on each level to unlock everything else...and upgrade ALL weapons.

Pro mode is difficult. Get infinite ammo for Rocket Launcher, the Hydra Shotgun and Lightning Hawk or the S &W Magnum. You should have no problem. Also have a bulletproof vest and the other vest. Carry herbs and first aid kit. I found it alot easier playing with a partner isntead of AI. The toughest part was Ndesu.

i played with people online who had the inf rocket launcher lol
I myself had just the inf Magnum S&W