Well I think the term system seller is misplaced because the vast majority of gamers don't buy a system just to play one game, they buy a system because there are at least few and maybe many different games they're interested in. GTA 3 and Vice City (and San Andreas to some extent) are often refered to as the biggest PS2 system sellers, but really what they were is games that pushed a lot of gamers over the edge to get a PS2 as they were already interested in other games for the system.
Look at the DS, is there really anything on that system that's the big system seller. No. Nintendogs, NSMB, Brain Age, Pokemon, Mario Kart, and Animal Crossing combine to make it one hell of an attractive system. Same goes for the PS1. There was no big selling game on the level of Mario 64 on that system, but Gran Turismo, plus Final Fantasy, plus Resident Evil, plus Crash Bandicoot, plus Driver, plus other games added up to an undeniably attractive lineup for millions upon millions of gamers at the time. We'll see a bump for 360 sales when Halo 3 comes, but not because people are buying the system just to play that game; I think 95% of people who do a buy a system to play Halo 3 are also interested in previously released 360 titles as well.