Picking top 5 is tough...my top 10 would be.
1. Uncharted 2
2. Last of Us
3. Batman: Arkham Asylum
4. Heavy Rain
5. Need for Speed: Hot Pursuit
6. Burnout Paradise
7. XCOM: Enemy Unknown
8. Final Fantasy 14: ARR
9. Skyrim
10. Bioshock
Other honorable mention goes to:
Assassin's Creed: Brotherhood
Rayman Origins
Resident Evil 5
Uncharted 1 &2
GTA 5
LA Noire
God of War series
Borderlands 2
Mafia 2
Rock Band 2
Fallout: New Vegas
Infamous
PixelJunk Monsters
Metal Gear Solid 4
Damn that's a long list and i'm missing some games too