"Nintendo is pleased to announce the acquisition of Valve"

Nintendo Steam - You know you want it.

I wouldn't put it past Ubisoft to put REd steel 2 on the 360 and PS3 considering how much time they're taking with it.

For me the best can be
1- hdd or sd support ( you can play your games of a sd i think that a sd of 4 GB for 20 euros it´s best that hdd of 20 for 100)

2 Many many games of third party GOOD support
3 The idea of red steel by free radical it´s the best i heard in all my life

Nintendo announcing the Wii Too, with HD capability and a slightly updated GameCube controller for release in 2009.

That's about as odd and unexpected as I can come up with, although RolStoppable's idea would be funnier.

Sony becomes 3rd party exclusive to the Wii.
Epic focuses on game play engines O.o
Majesco developes Killzone 3 on the Wii
Blizzard becomes Nintendo 2nd party
Activision is banned from the video game world by Nintendo
Microsoft turns into a peripheral company and they make faulty Wiimotes. (4 lights of death?)

Nintendo becomes 3 party software to Nintendo and 2nd party hardware developer to Nintendo, giving themselves an excuse to make Ubisoft level crap which in turn makes Ubisoft look better. Which in turn will make Nintendo 1st party stuff look amazing.

Also Sunny Bono skiing game using the balance board and a new impact detector.

(What? Too soon?)

Animal Crossing Wii will be displayed for the first time and it seems like a cross between Animal Crossing and Playstation Home; they will also announce Wii Paint and Wii Music which are both games/simulations of the activities and allow for user generated content that can be sared in Wii Paint, Wii Music and Animal Crossing Wii.

What I fully expect to see for Wii and DS all around:

Animal Crossing Wii as cross between Sims Online and an MMORPG with keyboard support.
Disaster: Day of Crisis (playable)
The Conduit (playable)
Mad World
Fatal Frame IV (playable)
Final Fantasy CC: Crystal Bearers (Playable)
Wii Music
Tenchu 4
Teaser for Factor 5's Kid Icarus game
Kirby Wii
At least two new franchise/surprise/announcements
Monster Lab
Monster Hunter 3 (playable)
Deadly Creatures (playable)
Red Steel 2
New Raving Rabbids Title
Final Fantasy IV remake for DS
Some older Nintendo franchise(s) suddenly revived besides Kid Icarus (Punch-Out, Mach Rider, Devil World, Earthbound/Mother, Excite Bike, Doshin the Giant, Stafy, Wild Gunmen/Hogan's Alley, Urban Champion, To The Earth, Startropics, Ice Climber, Pilotwings, Uniracers, etc)
Guitar Hero IV/Aerosmith/Metallica all for Wii with downloadable crap
Yet another Mario Party game
That stupid Mario Sluggers game
Sonic Unleashed
No fewer than 3 third party games that are newly revealed at E3; exclusives, mulitplatform--whatever.
Tons of DS RPG's, JRPG's, and Strategy games.
Moon for DS
Mushroom Men DS and Wii (playable)

A Massive Wii Ware showing with several playable titles, and more video demos.
At least one more classic console added to Virtual Console, or moved to new regions (ie, Commodore64 already in Europe, but to be added to US/Japanese VC).

What I sincerely hope we'll see, but doubt:

An announcement from Iwata that a memory/storage solution is underway allowing for external USB flash or harddrive use which reads directly from Channels menu.  Following this, size limits expanded for Wii Ware games.
Golden Sun 3 for DS
Mother 3 port or Mother collection for DS
Pikmin Wii or Pikmin DS teaser
Project HAMMER revived
Chrono Trigger-related announcement:  Either coming to VC, being ported to DS, or remade for DS
Eternal Darkness 2 for the Wii
Resident Evil Umbrella Chronicles 2 for the Wii
An exclusive RE game to make up for "not giving Wii RE5"
New Donkey Kong adventure.
New F-Zero
New, higher quality Custom Robo or some other originally Japan-only series being taken overseas
Rare or Bungie mysteriously developing or releasing something on an Nintendo system.  Perhaps Rare titles announced for VC.
Brand new Geist with online play.
Firmware update announced allowing of higher resolution "stretch" for Wii on HD-TV's.

I think Nintendo will, as they tend to do, come off as "winning E3" with a bigger show and more impressive and unexpected showpieces and announcements, but I don't believe there will be any word on yet another Metroid or Zelda title.  Potentially, Super Mario Galaxy 2 could be revealed.  Also, there will be no such talk as a Blu-Ray ready Wii, or of a Wii that plays DVD's.  I fear a new peripheral may be announced such as a camera or a microphone that plugs into the Wiimote.

Sadness gameplay footage?