Im excluding the PC from this because it just makes things messy and introduces too much fanboyism which doesnt belong in this thread.

 I'll try to update the list as people post games that they are excited about so we can make a sticky up in gaming for everyone to look at. We already have stickies for Exclusives, so why not the multiplats as well. So when we've got a big enough list i'll get some pictures and put together a blurb about each of the games.

Edit: I will try to add release dates later. I will check a few top upcoming game lists and cross reference with your lists. Also if a game comes up multiple times I will add it.

1.Alone in the dark 4. (All consoles)

2.Far Cry 2. (PS3, Xbox360)

3. Resident Evil 5. (PS3, Xbox360)

4. Star Wars - Force unleashed. (PS3, Xbox360, Wii, PS2 Afaik)

5. Fallout 3. (PS3, Xbox360)

6. Soul Calibur 5. (PS3, Xbox360)

7. End War. (PS3, Xbox360)

8. Protype (PS3, Xbox360)

9. Mercenaries 2: World in flames. (PS3, Xbox360)

10. Indiana Jones. (PS3, Xbox360)

Update 1. Added 6 more games removed COD5.

Not really sure about Call of Duty 5 tbh, it is done by Treyarch

my list:

MGS 4
FF XIII ....

real list:

Lord of the Rings Conquest (this could be amazing)
PES 2009 (the first proper next gen PES game)
Just Cause 2
Mercenaries 2
HAWX
Lego Batman
Indiana Jones
Soul Calibur 5
End War (could be great if it works well)

I think The Last Remnant has a chance of being quite good anyway... Then again that might just be the lack of JRPG's talking lol

consoles should be in parenthesis after the game title...

NCAA Football 2009 (PS3, 360, and Wii).

wet the game
resident evil 5
tomb raider underworld
prototype
grid
facebreaker
wheelman
bionic comando
new riddick game
operation flashpoint 2

mirror's edge 

I will add games to the list if they pop up in 2-3 peoples posts. Otherwise I will periodically check the list against previews etc to see if they're considered big games.

 Edit: I will also remove games if enough people say they dont belong.

Alright, then, I 2nd all of those.