it wouldnt be a problem if you were as un co-ordinated as a new born baby, there are games out there that requre you to use the nunchuck while moving the analogue stick, look at SSX blur for example, when you are snow boarding you use the analogue stick to stear and then rotate the nunchuck to carve, then when your doing tricks you use the the buttons on the nunchuck and tilt the nunchuck in 1 of 4 directions to do grabs while moving the analogue stick to do spins. And to make things even more hard core some uber tricks require you to draw shapes with both remotes at the same time, so mix that into the soup with the flips done with the normal remotes motion sensing and you have something that in theory is very complicated but is actually very easy to do in practice

 IT sounds coplicated , but if you say it's easy then I will take your word for it. 

It has a somewhat controlling idea that the game Crimsonland had. Crimsonland is alot easier, but the concept is the same.
Thanks Onyxmeth, there's probably tons more ideas from this. Although I'm not sure how much Nintendo would go for strangling customizable characters XD.