I dunno about that, especially if there can be multiple entrants from series and someone could convince activision to lease out certain iconic properties.

Ratchet and Clank as a tandem, Captain Qwark, Dr. Nefarious

Jak and Daxter tandem, Ashelin

Sly, Bently, Murray and Carmelita

Crash, Dr. Cortex, maybe Aku-Aku

Spyro, I can't really think of anyone else from that series that would be any good, maybe ripto

A hellghast and chimeran soldier, maybe Nathan Hale

Nathan Drake, VICTOR FRIGGIN SULLIVAN!, Chloe Frazer and or Elena Fisher

Cole McGrath (Kessler as an alt costume), Zeek, Delsin Rowe

Joel and Ellie tandem or individual, cordyceps zombie

Nariko from Heavenly Sword

Kratos, Zeus, Athena, Ares

Ico and the princess tandem, Wander

Fat Princess and knights

Sweet Tooth

The Journey thing

Sir Daniel Fortesque

Parappa, the sensei, maybe um jammer lammy but hopefully not

Some Ape escape character

Gabriel Logan

Sack Boy and maybe some of the new sack things coming in the new game

Norman Jayden, Jodei and Aiden tandem, obviously

That puppeteer puppet

Kat, Raven, maybe Alias from gravity rush

I could go on if you'd include characters typically associated with the playstation brand as nintendo is sort of doing with sonic, megaman and pacman

I think Nintendo fans care more about Capcom characters than Sony characters, probably the same goes for most videogame fans. Capcom must be the company with the most recognizable mascots after Nintendo.