Ultimate E3 wish? Probably an announcement that Nintendo has bought all of the old Rare IPs off Microsoft, and has enlisted the help of Warren Spector, Michel Ancel, and Crytek UK, along with Retro and Platinum Studios to make games for those various franchises (Platinum could have Conker, Michel Ancel could have Banjo, Spector could work with various older franchises, Crytek could work on Perfect Dark, and Retro could be offered their choice from any of the franchises).
In the more realistic category, an announcement that Nintendo has had various third parties holding back on announcements of their Wii U exclusive titles, including various franchises that people thought were on the backburner. Part of the deal involved was that every Wii U would ship with a download code for a non-Nintendo title of the customer's choice.
Into the category of actually realistic, there's an announcement of Mario & Sonic Adventure, for release in early 2015 (to avoid conflicting with Sonic Boom and Mario Galaxy U).