I beat the game and a few days ago and was just doing random things around the map and doing other things. But yesterday I noticed one of the map icons was gone, the strip club. I seen all it has to offer so it is less that than not being able to access a part of the game. Is anyone else having this problem? I may have to check the big map against the one in game to make sure I am not missing more. And outside of this and the social club problems things were mostly smooth for me in game. And here is a video showing the problem. http://youtu.be/ff7ZnJBe5cM

maybe it is the strip club which was owned by trevor.
As Trevor left Los Santos and some building can only be owned by special persons the icon dissappeared(that's one posdibility,or just a bug)

That is still his safe house. The link I posted shows me using franklin and then Trevor and the safe house icon is still there but I can not go inside with either of them. I just want to see if anyone else is having a problem with disappearing icons that cannot be entered into anymore.

Were you inside the building? I noticed last night that the icon for the building disappears if you enter it.

I am outside it.