Well, this seems a bit pointless, since the system isn't close to out, but I'll take a crack at it.
I think the concept is a bit bland, but workable. They seem to be pushing an emphasis on indie games (or at least the appearance of an emphasis on indie games) and simply providing a platform for publishers to make games on. Encouraging quantity, in that sense, and hoping quality comes from a solid foundation. If they have the right incentives, and a competitive online infrastructure, it could be a solid system. I'd love to compare it to the XBOne, but the concept for that machine seems to change month-to-month, so I won't even try to nail it down.
Execution...in terms of design, it seems alright. The new controller seems to be a good improvement over the last, and while I doubt the touchpad is going to see a whole lot of use, it opens up possibilities for some mobile games to make the transition, which comes back to quantity idea. There's no Nintendo-esqu evolution, partly I think because they're trying to perfect the wheel rather than reinvent it, though that leaves open the potential for staleness later in its lifetime.
In terms of the box, I'm of two minds. The slanted approach is actually something of a benefit for cables, I think, since they'll have overhead cover, instead of stick out where they can be bent if something presses on them, though that's a relatively minor problem. I do like it better than the PS3 design, with the straight edges and severe lines, as opposed to the more rounded, lop-sided predecessor. That said, it looks like it might be awkward to hold, and potentially taking up more space than the PS3, so we'll see.