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Forums - General - Scientists Created First Synthetic Cell

RockSmith372 said:
highwaystar101 said:
lestatdark said:
highwaystar101 said:
lestatdark said:
highwaystar101 said:

On topic: In case anyone is interested here is the paper.

I haven't read it yet, I will do it later. It's quite exciting that DNA can be synthetically produced, it really will open up a massive new area of research in Biology. The potential of this advance is phoenominal.

It isn't that mind-boggling actually. DNA in it's conception is a very simple molecule, made of a combination of four different Nucleotides which itself is separated into three parts: Phosphorous link, Sugar and Puryn/Pyrimidic base. Even Lipids and Proteins are more complex in it's conception than DNA

What's trully marvelous about DNA is the fact that it can hold all the information to create every molecule for a functional living being to exist. Just by pairing three simple nucleotide pairs into a codon to create aminoacids Nature's wonderfully simple in it's conception. 

I never said it was mind boggling . I know that the DNA isn't really that complicated and we can sequence a whole genome in a matter of days now. But what these people have done is an incredible breakthrough. It was very difficult logistically to produce an error free genome to transplant into the recipient cell, that's what's so great about this advance.

Yup, that's what I said on my first posts here

Being a student in biochemistry in the genomics field, this announcement was known for quite a while, but it trully stirred our university. Like Scoobes said, if we can somehow create, with a synthetic cell, a recombinant microorganism that has the same yield for genomic study as E.Coli or better, then a new age in genomics will unfold   

I haven't studied Biology since A-levels, so I can't really say. But as you said I really can imagine this really had a big impact on researchers and students alike. You're studying this field, it must be really exciting for you. As far as Biology goes I really only have a pop knowledge.

 

I'm in the same boat as highwaystar on this. I just finished high school and am going into Aerospace Engineering at Auburn University, but I am a huge fan of biology. Now that I just finished AP Biology, most of my information comes from a science journal called Nature. My dad has a PHD in Microbiology and is currently doing research to cure sickle cell, and he is a huge biology fan so I read the journal after he finishes with it. I heard about the synthetic cell on their website. My dad knew about this for weeks before but just failed to tell me until I already figured it out. It is a stepping stone to a new age in genomics.

Lol, you're probably pretty up to date then as Nature's probably the highest impact journal out there.



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lestatdark said:
SciFiBoy said:
reading about this in the paper this morning on the train, sounds interesting and like it has potential for the future, though from what I understand, this only proves the underlying theory, it doesnt in itself do anything that important just yet, im not a biologist though.

Actually this opens up a whole new field in genetics engineering. Previous to having a whole synthetic cell, the study of different mutation effects and study of genomic libraries, studies had to be done with use of generic bacteria like E.Coli, B.Subtilis, H.Influenza or with the use of genetically modified Yeasts (S.Cervisiae) using phages as vector mediums.

With this new technology, the entire synthetic DNA can be manipulated to provide the same yield of effects. We're talking about a whole chromossome that was man-made. That's literally millions of nucleotides arranged in a fashion that provides functionality for hundreds of genes and that can express the necessary building blocks (amino-acids and glucose-degrading enzymes) for that cell to grow. Now, with the advent of this technology, scientist can express the mutations and the study of different gene combinations on the chromossome itself.

oh I see, lol, like I said, I know very little about these things.