RE4 is the best third-person shooter/horror game ever made. I didn't want a half-assed attempt at a Gears of War clone. Also, Leon Kennedy wasn't in it, and he's the best male game character in existance (If I was gay (AND I'M NOT) I would mist likely be in love with Leon Kennedy). Also, the whole "supernatural" vibe from 4 was gone.
If RE5 has been on the Wii like RE4, it might have been better but not by much. I played the PC version hoping the controls would be like RE4 for the Wii, but they just sucked (still may better than playing it with a joy-pad though).
I'd give the game an 7.5/10. Not bad, but it could have been great.