The Persistence Enhanced complete.
This is a fairly easy platinum to get, and I reccomend it for anyone who wants a user-friendly rougelike, because skilling yourself up is something the game is very willing to allow. So, each run will naturally give you something (even if just skill points to use) to make the next run easier.
The only trophy that might take sometime is collecting 25 Supply Crates. Oh and a RNG one about killing an enemy with a trap mine - this one here if you find the mine you should definitely just reset the run so that you can find the mine in the same place.
Otherwise, rest is fairly easy.