I love this thread because I love the picks of pretty much everyone. The Wii was truly a special console...
To say something different, I LOVE Wario Land: The Shake Dimension. Best Wario Land game ever and one of the most beautiful games on the Wii, both visually and in its music. Besides that... It was just good fun!
Goldeneye 007 Remake was awesome too. I'm not much of an online guy, but I poured hundreds of hours into this. I was playing it sporadically as late as 2017-18. Sadly the servers went down...
And of course, Metroid Prime 3: Corruption. My favourite of the trilogy. I know, it's not a very popular take... But I just loved the slightly more action focus and traveling to different planets while keeping good old backtracking and puzzle solving for upgrades.