I’ll go first. (Highlighted are the nominees.)
1. Astro Bot [35% Winning Odds]
2. Final Fantasy VII Rebirth [>30% Winning Odds]
3. Elden Ring: Shadow of the Erdtree [<30% Winning Odds]
4. Metaphor: Fantasia [5% Winning Odds]
5. Silent Hill 2 Remake [0% Winning Odds]
6. Balatro [0% Winning Odds]
(Honorable Mentions: Black Myth: Wukong, Like A Dragon: Infinite Wealth, Animal Well, Zelda EoW.)
edit (11-16, @9:03am EST): Changed picks, added odds. Very close competition this year! Three-way tie for second place.
edit (11-17, @7:08pm EST): Adjusted odds. SotE is neck-and-neck with FFVIIReBirth, Astro Bots trails not too far behind, swapped Wukong for SH2R (i blame dave007 for convincing me to screw this call up), swapped Like A Dragon for Balatro.
edit (11-19, @8:39am EST): Adjusted odds. Astro is new favored, Metaphor falls behind.