Red Dead Redemption
Fallout 3
Metal Gear Solid 4
The Last of Us
Bioshock Infinite
Resident Evil 5
Metal Gear Rising Revengence
Batman Arkham Asylum
Batman Arkham Knight
Infamous 2
Dead Space 2 (and maybe 1)
Enslaved: Odyssey to the West
Uncharted 2 (and maybe 1)
Uncharted 3
Resistance 2 (and maybe 3)
Dead Island, Ni No Kuni, Fallout New Vegas & Modern Warfare 2 may make this list too.
I never got round to Playing God of War 3, Mass Effect Trilogy, Dishonoured 1 & 2, Demon/Dark Souls games. These would probably make the list too.
It's really hard to choose one because the 7th gen had so many great games particularly the PS3. I'd probably choose Red Dead Redemption, Fallout 3, The Last of Us, Metal Gear Solid 4 or Bioshock Infinite.
I remember voting for Red Dead Redemption for game of the generation, this was over 10 years ago now but it was still a hard choice.
I have (or have/had in the household): ZX Spectrum, Commodore 64, Amiga, NES, Sega Master System, Super Nintendo, Sega Megadrive, Gameboy, Playstation, Nintendo 64, Windows 95, Gameboy Colour, Windows 98, Sega Dreamcast, Gameboy Advance, PS2, Gamecube, Xbox, Windows XP, Nintendo DS, Xbox 360, Wii, PS3, Windows Vista, iPhone, Windows 7, 3DS, Wii U, PS4, Windows 10, PSVR, Switch, PS5 & PSVR2. :D
and I Don't have: Magnovox Odyssey, Any Atari's, Any Macintosh computers, Sega Gamegear, Virtual Boy, Sega Saturn, N-gage, Xbox One, Xbox Series X/S, PSP, PSVita & Andoid Phone. Plus any non-mainstream consoles/platforms I haven't mentioned.